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ANTI-MICROBIAL
7016
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INTRODUCTION-
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Anti-microbial 7016 is a newly developed organic antimicrobial
agent, that is very safe and highly effective for a wide range
of micro-organisms. It also has high heat and light resistance
when compared with general organic antimicrobial agents. In
addition, it will not stain most polymers,like inorganic Agtype
anti-microbial agents. It has wide application in various
fields, such as plastics,fibers,etc.
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Properties/Stability--
(1)Appearance......................Odorless white powder
(2)Tapped density................0.30(gr/cc)
(3)Thermostability(Air;10℃/min)
5% weight loss............441℃
10% weight loss.............455℃
20% weight loss.............465℃
(4)Photostability..............Stable
(5)pH Stability..................Stable(avoid contacting with strong
acid)
(6)Solubility.......................Partially soluble in alcohol,insoluble
in water and other organic solvents.
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Anit-microbial Activity(Minimum Inhibitory Concentration; MIC,ppm)-
Staphylococcus aureus.............31.2
Escherichia coli..........................250
Lactobacillus brevis ..................15.6
Aureobasidium pullulans...........250
Rhizopus stolonifer.....................62 |
MRSA........................................25
Bacillus subtilis.........................15.6
Aspergillus niger.......................500
Chaetomium globosum............250
Saccharomyces cerevisiae......62 |
Safety Data (main component) --
Acute oral toxicity............................LD50:>5000mg/kg(rats)
Subacute toxicity.............................No bad effects observed
on rats(administration of 500mg/kg for 90 days)
Ames test ........................................Negative
Chromosome aberration test ........None
Eye irritation.....................................None(rabbits)
Skin irritation....................................None(rabbits)
Fish bioaccumulation......................Low
Acute fish toxicity.............................LC50:>500ppm(killifish)
As described above in the safety data, Anti-Microbial 7016 is
a highly safe product and components are approved as an indirect
food additive by FDA 1),BGA 2),and JHOSPA 3),for use in food container
application. However,there is no regulation for anti-microbial agents
in FDA,BGA and JHOSPA,and therefore it is not listed as an anti-microbial
agent.
(1) Food and Drug Administration (US)
(2)Bundesgesundheitamt(Germany)
(3)Japan Hygienic Olefin and Stylene Plastics Association(Japan)
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Usage/Application -
Household electric appliances,Synthetic fibers,Construction materials,
Wrapping materials,Stationery and Toys etc.
*Typical concentration for use(Cell Viability:<0.1%)
PE..............................0.6%
PP..............................1.0%
ABS...........................1.5%
HIPS..........................1.0%
Caution-
1)Wear safety glasses,rubber gloves and a dust mask when handling.
2)In case of skin contact,immediately wash the affected area with
soap and water.
3)In case of eye contact,immediately rinse the eye with a copious
amount of water and consult a doctor.
The evaluation results for Anit-microbial
7016 test-
| Bacteria |
Sample |
Viable cells(cfu/ml) |
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| Escherichia coli |
(IFO 3972) |
Start |
After 24hrs |
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Control |
2.0×106 |
4.0×107 |
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none
7016
0.3 phr
0.6 phr |
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5.0×107
3.0×104
<102 |
| Staphylococcus aureus |
(IFO 12732) |
Start |
After 24hrs |
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Control |
1.0×106 |
2.0×105 |
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none
7016:
0.3 phr
0.6 phr |
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5.0×105
2.0×103
<102 |
*Sample:HDPE sheet with or without 7016
*Control:Plastic Petri dish
*<102 :not detected
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